Pathology MCQ 11
Pathology MCQ 11:
A 76-year-old man has had a slowly enlarging nodule on his right eyelid for 4 years. On physical examination, there is a 0.3-cm pearly nodule on the upper eyelid near the lateral limbus of the right eye. The lesion is excised, but multiple frozen sections are made during the surgery to minimize the extent of the resection and preserve the eyelid. The microscopic appearance of the lesion is shown in the figure. What is the most likely diagnosis?
A Actinic keratosis
B Basal cell carcinoma
C Dermatofibroma
D Malignant melanoma
E Nevocellular nevus
Explanation:
Basal cell carcinomas arise as pearly papules on sun exposed areas of the skin, particularly the face. They slowly infiltrate surrounding tissues, gradually enlarging. Although
it rarely metastasizes, a basal cell carcinoma can have serious local effects, particularly in the area of the eye.
An actinic keratosis is a premalignant lesion of the epidermis that does not invade surrounding tissue.
A dermatofibroma is a benign lesion of the dermis composed of cells resembling fibroblasts.
Melanomas are usually pigmented, and they are composed of polygonal or spindle cells that tend to grow in sheets and infiltrate to produce a grossly irregular border to
the lesion.
A nevus is a small, localized, benign lesion
So, the correct option is B.
(P.C-Mrcopath)
A 76-year-old man has had a slowly enlarging nodule on his right eyelid for 4 years. On physical examination, there is a 0.3-cm pearly nodule on the upper eyelid near the lateral limbus of the right eye. The lesion is excised, but multiple frozen sections are made during the surgery to minimize the extent of the resection and preserve the eyelid. The microscopic appearance of the lesion is shown in the figure. What is the most likely diagnosis?
A Actinic keratosis
B Basal cell carcinoma
C Dermatofibroma
D Malignant melanoma
E Nevocellular nevus
Explanation:
Basal cell carcinomas arise as pearly papules on sun exposed areas of the skin, particularly the face. They slowly infiltrate surrounding tissues, gradually enlarging. Although
it rarely metastasizes, a basal cell carcinoma can have serious local effects, particularly in the area of the eye.
An actinic keratosis is a premalignant lesion of the epidermis that does not invade surrounding tissue.
A dermatofibroma is a benign lesion of the dermis composed of cells resembling fibroblasts.
Melanomas are usually pigmented, and they are composed of polygonal or spindle cells that tend to grow in sheets and infiltrate to produce a grossly irregular border to
the lesion.
A nevus is a small, localized, benign lesion
So, the correct option is B.
(P.C-Mrcopath)
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