Melamed-Wolinska bodies
Melamed-Wolinska bodies:
Awesome picture showing Cytoplasmic inclusions (Melamed-Wolinska bodies).Degenerating urothelial cells frequently have round, eosinophilic (or sometimes green) cytoplasmic inclusions of varying sizes. A normal columnar-shaped urothelial cell is also present.........
When degenerated, urothelial cells resemble histiocytes in urine sample, especially because they sometimes contain round, red, or green hyaline cytoplasmic inclusions called Melamed-Wolinska bodies. They are seen in almost 50% of urine specimens and are more common in voided as opposed to catheterized samples. The pathogenesis of these bodies is obscure, and they have no diagnostic value in urine, but they are useful in suggesting a urothelial origin for malignant cells in pleural effusions.(Ref:Cytology, Cibas & Ducatmann).
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Awesome picture showing Cytoplasmic inclusions (Melamed-Wolinska bodies).Degenerating urothelial cells frequently have round, eosinophilic (or sometimes green) cytoplasmic inclusions of varying sizes. A normal columnar-shaped urothelial cell is also present.........
When degenerated, urothelial cells resemble histiocytes in urine sample, especially because they sometimes contain round, red, or green hyaline cytoplasmic inclusions called Melamed-Wolinska bodies. They are seen in almost 50% of urine specimens and are more common in voided as opposed to catheterized samples. The pathogenesis of these bodies is obscure, and they have no diagnostic value in urine, but they are useful in suggesting a urothelial origin for malignant cells in pleural effusions.(Ref:Cytology, Cibas & Ducatmann).
If you like, you can visit our youtube channel and facebook page👇🏻
Youtube channel link-https://m.youtube.com/channel/UCPGvHc5Ttw4EtB72WVMiYSw/videos
Facebook page link-https://m.facebook.com/PathologyDiscussionForum/?ref=bookmarks
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