Rosenthal fiber

Rosenthal fiber:
A Rosenthal fiber is a thick, elongated, worm-like or "corkscrew" eosinophilic (pink) bundle that is found on H&E staining of the brain in the presence of long-standing gliosis, occasional tum

ors, and some metabolic disorders. The fibers are found in astrocytic processes and are thought to be clumped intermediate filament proteins. Their components include glial fibrillary acidic protein.